Complexity Science Seminar Series - Abstracts
Title:
Data Integration for Dynamic and Sustainable Systems Biology Resources: Challenges and Lessons
Presenter:
Dan Sullivan, Senior Database Architect, Virginia Bioinformatics Institute
Date and Time: Monday, August 24th, 2009, 2:00pm-3:00pm
Abstract:
Systems biology and host-pathogen research is increasingly dependent on integrating data from diverse sources. Maintaining integrated resources over long periods of time presents distinct challenges. This talk describes experiences and lessons learned from integrating data in two five-year projects focused on pathosystems biology: the Pathosystems Resource Integration Center (PATRIC, http://patric.vbi.vt.edu/), with a goal of developing bioinformatics resources to the research community based on genomics data, and the Biodefense Proteomics Resource Center (RBPRC, http://www.proteomicsresource.org), with goal of developing resources based on the experiment data such as microarrays and proteomics data from diverse sources. Some challenges include: integrating genomic sequence and experiment data, data synchronization, data quality control, graceful degradation, and exposing metadata. We present examples of a variety of data integration problems drawn from our experiences with PATRIC and RBPRC as well as open research questions related to long term sustainability and describe next steps to meeting these challenges.
Seminar Location: The seminar will be held at:
Virginia Tech, Corporate Research Center
1880 Pratt Drive, Building XV
Seminar Room, First Floor
Directions: Map (PDF)
Back to: NDSSL Seminar Page